Противодиарейное свойство– exhibits intestinal anti-secretory activity.
Anti-ulcer activity – significantly decreases gastric lesions.
Anti-hyperlipidemic activity – surpasses triglyceride synthesis in liver through inhibition of fatty acid synthase; reduces serum triglyceride, total cholesterol and LDL levels; decreases cholesterol absorption and affects HMG-CoA reductase.
Anti-obesity effect – shows to cause decrease in body weight and improve serum lipid profile.
Anti-diabetic effect – mildly reduces plasma glucose levels; increases tissue sensitivity towards insulin; inhibits diabetes-induced inflammatory processes; improves lipid profile.
Nephroprotective effect – produces vasodilation and increases blood flow in kidneys; reduces oxidative stress.
Effect on preeclampsia – shows protective effect on endothelial cells of preeclamptic patients.
Hepatoprotective effect – due to its antioxidant and anti-inflammatory effects as well as inhibition of collagen synthesis, shows to protect against liver fibrosis.
Ergogenic effect – shows to enhance vessel diameter, blood flow and delay fatigue during exercises.
Anti-atherosclerotic effect – protects endothelial function, improves lipid profile.
Anti-hypertensive effect – inhibits serum angiotensin converting enzyme (ACE) and decreases systolic blood pressure.
Cardioprotective effect – prevents cardiac damage; reduces myocardial ischemia and improves myocardial perfusion; shows significant therapeutic value in prophylactic treatment of myocardial infarction.

Антибактериальная активность – shows antibacterial activity (against Proteus spp., H.influenza, Klebsiella pneumoniae, Pseudomonas aeruginosa, Streptococcus spp., Staphylococcus aureus, Enterocuccus faecalis, E.coli); anti-fungal activity (Candida albicans, Trichophyton spp.); antiviral activity (against genital herpes virus, Herpes simplex virus, hepatitis B virus, hepatitis C virus); anti-parasitic activity (Taenia spp., Ascaris lumbricoides); shows to inhibit oral pathogens.
Иммуномодулирующее действие
Противовоспалительное действие - снижает уровень провоспалительных цитокинов; ингибирует COX, LOX.
Противоакневое действие - подавляет рост акне-зависимых бактерий; снижает выработку кожного сала за счет снижения активности липазы; ослабляет воспалительный статус; предотвращает чрезмерное распространение кератиноцитов.
Антиостеопоротическое действие – shows to promote bone cell proliferation and differentiation in primary osteoblasts; inhibits bone resorption process.
Anti-rheumatoid arthritis effect – exhibits anti-inflammatory effect; prevents development of joint damage; prevents maintenance and development of inflammation in RA; reduces severity and incidence of joint inflammation; inhibits cartilage degradation; helps to maintain joint integrity and function.
Antioxidant activity – inhibits lipid peroxidation; protects from oxidative stress; has free radical scavenging activity.
Neuroprotective activity – inhibits cholinesterase activity; prevents accumulation of lipid in brain; protects brain from stress oxidant; protects against cerebral ischemia-reperfusion induced oxidative brain injury; inhibits learning and memory deficits and neuronal cell death caused by amyloid-beta-induced oxidative stress; thus may be beneficial for prevention, management and supportive treatment of neurodegenerative diseases; shows to reduce neuropathic pain in acquired peripheral neuropathy.
Anti-cancer activity – shows to be chemopreventive/ chemotherapeutic agent; exhibits anti-inflammatory, anti-proliferative and anti-tumorigenic effects on skin, breast, prostate, lung and colon cancers.

Омоложение:
Балансирует нарушения холода и Ветра
Укрепляет лёгкие
Восстанавливает физическую силу и тепло
Повышает либидо и потенцию
Поддерживает функцию сердца
Лечит анемию

Желудочно-кишечный тракт:
Восстанавливает пищеварительное тепло
Облегчает несварение желудка
Снижает кислотность желудка
Снимает раздражение желудочно-кишечного тракта
Регулирует аппетит
Прекращает тошноту и рвоту
Останавливает диарею
Облегчает запор
Устраняет жажду и сухость
Заживляет язвы во рту и желудочно-кишечном тракте
Облегчает геморрой
Очищает от паразитов

Мочевыделительная система:
Укрепляет почки
Снимает вагинальную инфекцию
Нормализует менструальный цикл

Иммунная система и детоксикация:
Снимает лёгочную лтихорадку
Излечивает от бронхита и других инфекций дыхательных путей
Снимает одышку
Укрепляет иммунную систему
Очищает кожу

• WHO monograph Pericarpium Granati
• WHO monograph Cortex Granati
• Effects of Pomegranate (Punica Granatum L.) Seed and Peel Methanolic Extracts on Oxidative Stress and Lipid Profile Changes Induced by Methotrexate in Rats
• Consumption of Hydrolyzable Tannins Rich Pomegranate Extract (POMx) Suppresses Inflammation and Joint Damage In Rheumatoid Arthritis
• The effects of pomegranate extract on normal adult rat kidney: A stereological study
• Protective effects of extracts from Pomegranate peels and seeds on liver fibrosis induced by carbon tetrachloride in rats
• A Comprehensive Review of Punica granatum (Pomegranate) Properties in Toxicological, Pharmacological, Cellular and Molecular Biology Researches
• Therapeutic Applications of Pomegranate (Punica granatum L.): A Review Alternative Medicine Review Volume 13, Number 2 2008
• Attenuating effect of standardized fruit extract of punica granatum L in rat model of tibial and sural nerve transection induced neuropathic pain
• The effects of pomegranate extract on blood flow and running time to exhaustion
• Inhibitory Effect of the Punica granatum Fruit Extract on Angiotensin-II Type I Receptor and Thromboxane B2 in Endothelial Cells Induced by Plasma from Preeclamptic Patients
• Osteogenic potential of punica granatum through matrix mineralization, cell cycle progression and runx2 gene expression in primary rat osteoblasts
• Pomegranate for Prevention and Treatment of Cancer: An Update
• “Rhetoric to Reality”- Efficacy of Punica Granatum Peel Extract on Oral Candidiasis: An in vitro Study
• Effect of pomegranate extracts on brain antioxidant markers and cholinesterase activity in high fat-high fructose diet induced obesity in rat model
• Cardioprotective potential of Punica granatum extract in isoproterenol-induced myocardial infarction in Wistar rats
• Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV